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Journal : e-Journal Pustaka Kesehatan

Prevalensi, Karakteristik dan Faktor-faktor yang Berhubungan dengan Penyakit Skabies di Pesantren Nurul Qarnain Kabupaten Jember (The Prevalence, Characteristic and Factors of Scabies in Pesantren Nurul Qarnain Jember) Ika Rahmawati Sutejo; Viddy Agustian Rosyidi; Alief Ilman Zaelany
Pustaka Kesehatan Vol 5 No 1 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Scabies is a common skin disease caused by infection of Sarcoptes scabei, which is transmitted directly human-to-human contact especially in crowded community like pesantren. The characteristics of the students in pesantren are seemingly to be associated with Scabies. The purpose of this study was to determine the prevalence, characteristics of Scabies and its association with gender and education level of students in Pesantren Nurul Qarnain Jember. This cross sectional study was conducted to all students (1120 students) in 2016. Diagnosis was made based on anamnesis and dermatology examination. Data were analyzed using chi square test. The results showed that the prevalence of Scabies was 13.48% (male 24.89% and female 5.82%; education level tsanawiyah 15.14.1% and aliyah 10.85%). Most lesions were found in the interdigital space of the hands (40.40%). Chi square test showed significant difference between the prevalence of Scabies with gender (p=0.048) and education level (p=0.023) of the students. In conclusion, the prevalence of Scabies in Pesantren Nurul Qarnain Jember was 13.48% and there was association between the prevalence of Scabies with gender and education level of the students.  Keywords: Scabies, prevalence, students, gender, educational level
Aktivitas Membran Bakiko (Bayam-Kitosan-Kolagen) terhadap Ekspresi Matriks Metaloproteinase-9 pada Luka Bakar Derajat II Hazmi Dwinanda Nurqistan; Al Munawir; Ika Rahmawati Sutejo
Pustaka Kesehatan Vol 7 No 1 (2019): Volume 7 No. 1, 2019
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.19184/pk.v7i1.17593

Abstract

Matrix metalloproteinase-9 (MMP-9) plays an important role in regulating the degradation and deposition extracellular matrix (ECM) that are important for wound reepithelization. However, excessive protease activity can lead to delayed wound healing. Kaemferol in spinach can inhibit the activity of MMP-9. Chitosan and collagen can help tissue growth and have an antimicrobial effect. Chitosan-collagen membranes have been widely used for wound healing but, the results are unsatisfactory. Therefore, the researcher wanted to know the activity of bakiko (Spinach-Chitosan-Collagen) membrane to MMP-9 expression on second degree burn with immunohistochemical method. This research was true-experimental laboratories design with post test only control group design. The experimental animals used were 36 white wistar rats (Rattus novergicus) male, divided into 4 groups ie control group, negative control, positive control (bioplacenton), and treatment (bakiko membrane). Data were obtained by calculating MMP-9 using ImageJ software. The analysis using anova test showed that p value less than 0.05 indicated a significant difference. This study showed that there was a decrease in MMP-9 activity by bakiko membrane in grade II burn with immunohistochemical method in wistar rats.
Efektivitas Analgesik Kombinasi Parasetamol dan Ekstrak Kasar Nanas terhadap Refleks Geliat Mencit yang Diinduksi Asam Asetat (The Analgesics Effectivity of Combination of Paracetamol and Pineapple Crude Extract on Writhing Reflex in Mice Induced by Ace Fauqi Amalia; Cholis Abrori; Ika Rahmawati Sutejo
Pustaka Kesehatan Vol 5 No 3 (2017)
Publisher : UPT Percetakan dan Penerbitan Universitas Jember

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Abstract

Bromelain is a proteolytic enzyme which can be found in pineapple. The proteolytic activity of bromelain commonly used as an anti-inflammatory agent and antioedema, antithrombotic, and fibrinolytic agent. This study aimed at determining the combination effectivity of paracetamol and bromelain, pineapple crude extract’s protein, on pain response in mice and its interaction. This research used true experimental design with posttest only control group. Data analysis using Kruskal-Wallis test and application CompuSyn. The mice induced by acetic acid as the pain’s trigger and writhing reflex calculated every 5 minutes for 1 hour. The results of this study were expressed by pain protection persentage of paracetamol, crude extract of pineapple, a combination dose of paracetamol and crude extract of pineapple ½:½ and 1:1 was 52.23 ± 3.94%; 51.28 ± 6.71%; 77.88 ± 4.02%; and 71.24 ± 10.54%. The results of the CompuSyn dose combination analysis showed a synergistic effect that is seen from the CI value. In conclusion, analgesic effectivity combination of paracetamol and pineapple crude extract more effective than single dose usage and showed a synergistic effect. Keywords: analgesic, bromelain, pain, paracetamol, pineapple